Description
Product Characteristics: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of erythroferrone in human serum, plasma, tissue homogenates, cell lysates, cell culture supernates.
Target Information: Iron-regulatory hormone that acts as an erythroid blood loss and mediates suppression of hepcidin (HAMP) expression in the liver, thereby promoting increased iron absorption and mobilization from stores. Promotes lipid uptake into adipocytes and hepatocytes via transcriptional up-regulation of genes involved in fatty acid uptake. {ECO:0000250:UniProtKB:Q6PGN1, ECO:0000269:PubMed:22351773}